International Clinical Trials Day 20 May 2013

ok to ask14 May 2013

International Clinical Trials Day 2013 will be held on Monday (20 May) to commemorate the anniversary of the first clinical trial conducted by James Lind. The day aims to raise the profile of clinical research taking place in the NHS. 

This year’s campaign is focusing on encouraging patients to ask about opportunities to participate in research. Please visit www.crncc.nihr.ac.uk/oktoask to find out more.

The London Ambulance Service is committed to participate in research to ensure that we deliver the best possible care to our patients.

Examples of our current or recent clinical research projects include:

DART: Dispatcher-assisted resuscitation trial
This trial investigated whether chest compressions plus ventilations (standard CPR) or chest compressions alone improved survival from cardiac arrest. The DART study contributed to the evidence base that informed the British Heart Foundation’s recent campaign with Vinnie Jones to promote ‘hands-only’ CPR.

ISRAS: Improving stroke recognition by ambulance services
All UK ambulance services use the Face Arm Speech Test (FAST) to assess suspected stroke patients. This study aimed to investigate whether the use of the recognition of stroke in the emergency room (ROSIER) tool could improve stroke recognition by ambulance clinicians. The study found that the ROSIER was not better than the FAST for pre-hospital recognition of stroke.

DANCE: Direct angioplasty for non-ST-elevation acute coronary (heart attack) events
Patients with non-ST-elevation acute coronary syndromes (heart attack) are typically taken to their local emergency department where they receive medical stabilisation and undergo angiography. This randomised controlled pilot study aims to compare immediate assessment and treatment with standard care for patients with high risk non-ST-elevation acute coronary syndromes. The study is also investigating whether trained ambulance clinicians can correctly identify patients with non-ST-elevation acute coronary syndromes. The study is led by the Service’s Consultant Paramedic Mark Whitbread.

ParaSVT: Safety and efficacy of paramedic treatment for regular supraventricular tachycardia (abnormally fast heart beat)
Some types of regular supraventricular tachycardias (SVT), abnormally fast heart beat, are common but not dangerous, although the symptoms may be both unpleasant and frightening for patients. This randomised controlled trial is investigating whether trained paramedics can safely treat and discharge patients with SVT. Patients are randomly allocated to either receive paramedic treatment with adenosine on scene or conveyance to their local emergency department (standard treatment).

SAFER2: Support and assessment for fall emergency referrals
This randomised controlled trial aims to measure the costs and benefits of a protocol allowing ambulance clinicians to assess and refer older people who fall to community-based fall services. Over 4,000 patients have been recruited into the study by paramedics from three ambulance services, with more than 350 patients being referred to community falls services. Follow-up data is currently being collected from patients and hospitals to assess the impact of the new protocol and referral pathway.

For further information, please contact the clinical audit & research unit on 020 7783 2504 or at [email protected]